Norgene Rapid ac4C RNA Enrichment Kit

Cat.# 0004

RNA N4-acetylcytidine (ac4C) is the acetylation of cytidine at the nitrogen-4 position, which is a highly conserved RNA modification and involves a variety of biological processes^1,2.

The Norgene Rapid ac4C RNA Enrichment Kit is simple and rapid workflow to enable identification and profiling of ac4C (N4-acetylcytidine) RNA acetylation sites at transcriptome-wide level. Suitable for downstream RNA library construction and sequencing or qRT-PCR to check acetylated RNA transcripts.

HIGHLIGHTS

• Simple workflow: From beginning to end the protocol can be completed in just one day.
• Accurate and reproducible: Innovative immunoprecipitation and elution technology ensure efficient and reproducible results across replicates.

References

1. Gehui Jin, Mingqing Xu, Mengsha Zou, Shiwei Duan, The Processing, Gene Regulation, Biological Functions, and Clinical Relevance of N4-Acetylcytidine on RNA: A Systematic Review, Molecular Therapy - Nucleic Acids, 2020

2. Daniel Arango, et al., Acetylation of Cytidine in mRNA Promotes Translation Efficiency, Cell, 2018